GO Term : GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing GO

Namespace:  cellular_component Obsolete:  false
description  A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

5 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0055052 37443.t000002  
OntologyAnnotation GO:0055052 37443.m000021 GO
GOAnnotation GO:0055052 IPR022473  
GOAnnotation GO:0055052 IPR030165  
GOAnnotation GO:0055052 IPR030166  

20 Parents

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0005886 plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0043190 ATP-binding cassette (ABC) transporter complex A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.
GO:0031224 intrinsic component of membrane The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane.
GO:1902494 catalytic complex A protein complex which is capable of catalytic activity.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0071944 cell periphery The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
GO:0098796 membrane protein complex Any protein complex that is part of a membrane.
GO:0044425 membrane part Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0098797 plasma membrane protein complex Any protein complex that is part of the plasma membrane.
GO:0044459 plasma membrane part Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:1990351 transporter complex A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.
GO:1902495 transmembrane transporter complex A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.
GO:0098533 ATPase dependent transmembrane transport complex A transmembrane protein complex that functions in ATPase dependent active transport across a membrane.

22 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0043190 GO:0055052
part of GO:0044464 GO:0055052
part of GO:0016020 GO:0055052
is_a GO:0032991 GO:0055052
part of GO:0016021 GO:0055052
is_a GO:0005575 GO:0055052
is_a GO:1990351 GO:0055052
is_a GO:0044425 GO:0055052
is_a GO:0044459 GO:0055052
is_a GO:0098796 GO:0055052
part of GO:0071944 GO:0055052
is_a GO:0098797 GO:0055052
is_a GO:0098533 GO:0055052
part of GO:0031224 GO:0055052
is_a GO:0044464 GO:0055052
is_a GO:0043234 GO:0055052
part of GO:0005623 GO:0055052
part of GO:0005886 GO:0055052
part of GO:0005575 GO:0055052
is_a GO:1902495 GO:0055052
is_a GO:1902494 GO:0055052
part of GO:0044425 GO:0055052

0 Synonyms