GO Term : GO:0045122 aflatoxin biosynthetic process GO

Namespace:  biological_process Obsolete:  false
description  The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

3 Ontology Annotations

Class GO Term Gene Name Db
OntologyAnnotation GO:0045122 Oeu029691.1 GO
GOAnnotation GO:0045122 Oeu029691.1  
GOAnnotation GO:0045122 IPR013700  

26 Parents

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0045122 aflatoxin biosynthetic process The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving organic cyclic compound.
GO:0046483 heterocycle metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0044711 single-organism biosynthetic process A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - involving a single organism.
GO:1901576 organic substance biosynthetic process The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.
GO:1901362 organic cyclic compound biosynthetic process The chemical reactions and pathways resulting in the formation of organic cyclic compound.
GO:0018130 heterocycle biosynthetic process The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
GO:0019748 secondary metabolic process The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
GO:0044550 secondary metabolite biosynthetic process The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
GO:0009404 toxin metabolic process The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
GO:0009403 toxin biosynthetic process The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
GO:1901376 organic heteropentacyclic compound metabolic process The chemical reactions and pathways involving organic heteropentacyclic compound.
GO:1901378 organic heteropentacyclic compound biosynthetic process The chemical reactions and pathways resulting in the formation of organic heteropentacyclic compound.
GO:0043385 mycotoxin metabolic process The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus.
GO:0043386 mycotoxin biosynthetic process The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus.
GO:0046222 aflatoxin metabolic process The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.

33 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0043386 GO:0045122
is_a GO:1901378 GO:0045122
is_a GO:0046222 GO:0045122
is_a GO:0044550 GO:0045122
is_a GO:0043385 GO:0045122
is_a GO:0046483 GO:0045122
is_a GO:0018130 GO:0045122
is_a GO:0071704 GO:0045122
is_a GO:0019748 GO:0045122
is_a GO:0009058 GO:0045122
is_a GO:1901376 GO:0045122
is_a GO:1901576 GO:0045122
is_a GO:1901360 GO:0045122
is_a GO:0008150 GO:0045122
is_a GO:1901362 GO:0045122
is_a GO:0008152 GO:0045122
is_a GO:0009403 GO:0045122
is_a GO:0044763 GO:0045122
is_a GO:0009404 GO:0045122
is_a GO:0009987 GO:0045122
is_a GO:0044237 GO:0045122
is_a GO:0044710 GO:0045122
is_a GO:0044699 GO:0045122
is_a GO:0044249 GO:0045122
is_a GO:0044711 GO:0045122
regulates GO:0045122 GO:1900177
regulates GO:0045122 GO:1900177
negatively regulates GO:0045122 GO:1900178
negatively regulates GO:0045122 GO:1900178
regulates GO:0045122 GO:1900178

4 Synonyms

Name Type
aflatoxin anabolism synonym
aflatoxin biosynthesis synonym
aflatoxin formation synonym
aflatoxin synthesis synonym