GO Term : GO:0005579 membrane attack complex GO

Namespace:  cellular_component Obsolete:  false
description  A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

9 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0005579 Gohir.A05G159600  
OntologyAnnotation GO:0005579 Gohir.A05G159600.1.p GO
GOAnnotation GO:0005579 AH012471  
OntologyAnnotation GO:0005579 AH012471-RA GO
GOAnnotation GO:0005579 EL10Ac7g17078  
OntologyAnnotation GO:0005579 EL10Ac7g17078.1 GO
GOAnnotation GO:0005579 Thupl.29377975s0005  
OntologyAnnotation GO:0005579 Thupl.29377975s0005.1.p GO
GOAnnotation GO:0005579 IPR001862  

18 Parents

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0005886 plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0005887 integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0046930 pore complex Any small opening in a membrane that allows the passage of gases and/or liquids.
GO:0031224 intrinsic component of membrane The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane.
GO:0005579 membrane attack complex A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0071944 cell periphery The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
GO:0098796 membrane protein complex Any protein complex that is part of a membrane.
GO:0044425 membrane part Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0098797 plasma membrane protein complex Any protein complex that is part of the plasma membrane.
GO:0044459 plasma membrane part Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0031226 intrinsic component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.

21 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0005887 GO:0005579
is_a GO:0046930 GO:0005579
is_a GO:0098797 GO:0005579
part of GO:0031226 GO:0005579
is_a GO:0043234 GO:0005579
is_a GO:0044425 GO:0005579
part of GO:0005886 GO:0005579
is_a GO:0044459 GO:0005579
part of GO:0005623 GO:0005579
is_a GO:0044464 GO:0005579
is_a GO:0098796 GO:0005579
part of GO:0031224 GO:0005579
part of GO:0044425 GO:0005579
is_a GO:0005575 GO:0005579
part of GO:0071944 GO:0005579
part of GO:0044459 GO:0005579
part of GO:0016020 GO:0005579
part of GO:0016021 GO:0005579
is_a GO:0032991 GO:0005579
part of GO:0044464 GO:0005579
part of GO:0005575 GO:0005579

5 Synonyms

Name Type
MAC synonym
membrane attack complex protein alphaM chain synonym
membrane attack complex protein beta2 chain synonym
TCC synonym
terminal complement complex synonym