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GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
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GO:0005515
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protein binding
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Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
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GO:0004672
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protein kinase activity
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Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. |
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GO:0006468
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protein phosphorylation
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The process of introducing a phosphate group on to a protein. |
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GO:0005488
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binding
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The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
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GO:0016310
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phosphorylation
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The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
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GO:0016772
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transferase activity, transferring phosphorus-containing groups
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Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). |
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GO:0008152
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metabolic process
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The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. |
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GO:0006796
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phosphate-containing compound metabolic process
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The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. |
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GO:0044237
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cellular metabolic process
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The chemical reactions and pathways by which individual cells transform chemical substances. |
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GO:0051726
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regulation of cell cycle
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Any process that modulates the rate or extent of progression through the cell cycle. |
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GO:0019901
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protein kinase binding
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Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. |
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GO:0016301
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kinase activity
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Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. |
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GO:0016773
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phosphotransferase activity, alcohol group as acceptor
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Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). |
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GO:0016538
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cyclin-dependent protein serine/threonine kinase regulator activity
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Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins. |
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GO:0019538
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protein metabolic process
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The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification. |
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GO:0016740
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transferase activity
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Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
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GO:0004857
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enzyme inhibitor activity
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Binds to and stops, prevents or reduces the activity of an enzyme. |
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GO:0030234
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enzyme regulator activity
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Binds to and modulates the activity of an enzyme. |
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GO:0004674
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protein serine/threonine kinase activity
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Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
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GO:0019887
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protein kinase regulator activity
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Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein. |
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GO:0006464
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cellular protein modification process
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The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). |
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GO:0071704
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organic substance metabolic process
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The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. |
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GO:0004861
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cyclin-dependent protein serine/threonine kinase inhibitor activity
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Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase. |
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GO:0043412
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macromolecule modification
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The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. |
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GO:0044238
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primary metabolic process
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The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
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GO:0001932
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regulation of protein phosphorylation
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Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. |
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GO:0050790
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regulation of catalytic activity
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Any process that modulates the activity of an enzyme. |
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GO:0043086
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negative regulation of catalytic activity
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Any process that stops or reduces the activity of an enzyme. |
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GO:0045859
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regulation of protein kinase activity
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Any process that modulates the frequency, rate or extent of protein kinase activity. |
