Protein Domain : IPR017251

Type:  Family Name:  Apoptotic protease-activating factor 1
Description:  Apoptotic protease activating factor-1 (Apaf-1) is a component protein of the apoptosome []. During apoptosis, cytochrome c is released from mitochondria to the cytosol and binds Apaf-1. Binding of cytochrome c to Apaf-1 allows the recruitment and activation of caspase-9 within the apoptosome []. Short Name:  Apaf-1
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0 Child Features

7 Contains

DB identifier Type Name
IPR015943 Domain WD40/YVTN repeat-like-containing domain
IPR001680 Repeat WD40 repeat
IPR017986 Domain WD40-repeat-containing domain
IPR020472 Repeat G-protein beta WD-40 repeat
IPR002182 Domain NB-ARC
IPR001315 Domain CARD domain
IPR019775 Conserved_site WD40 repeat, conserved site

1 Cross References

Identifier
PIRSF037646

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0097190 IPR017251
GO:0043293 IPR017251

2 Ontology Annotations

GO Term Gene Name
GO:0097190 IPR017251
GO:0043293 IPR017251

0 Parent Features

0 Proteins

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            18439902
            24651435