GO Term : GO:0006898 receptor-mediated endocytosis GO

Namespace:  biological_process Obsolete:  false
description  An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

6 Ontology Annotations

GO Term Gene Name
GO:0006898 IPR003543
GO:0006898 IPR026296
GO:0006898 IPR026814
GO:0006898 IPR028876
GO:0006898 IPR029513
GO:0006898 IPR029923

12 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0016192 vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
GO:0006897 endocytosis A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
GO:0061024 membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
GO:0010324 membrane invagination The infolding of a membrane, resulting in formation of a vesicle.
GO:0006898 receptor-mediated endocytosis An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.

89 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0006898 GO:0002031
regulates GO:0006898 GO:0002090
negatively regulates GO:0006898 GO:0002091
regulates GO:0006898 GO:0002091
positively regulates GO:0006898 GO:0002092
regulates GO:0006898 GO:0002092
part of GO:0006898 GO:0004873
part of GO:0006898 GO:0004998
part of GO:0006898 GO:0005041
part of GO:0006898 GO:0005044
is_a GO:0006897 GO:0006898
has_part GO:0008150 GO:0006898
is_a GO:0006810 GO:0006898
is_a GO:0051234 GO:0006898
has_part GO:0061024 GO:0006898
is_a GO:0051179 GO:0006898
has_part GO:0071840 GO:0006898
has_part GO:0010324 GO:0006898
is_a GO:0016192 GO:0006898
has_part GO:0016043 GO:0006898
has_part GO:0009987 GO:0006898
is_a GO:0008150 GO:0006898
part of GO:0006898 GO:0008196
part of GO:0006898 GO:0016964
is_a GO:0006898 GO:0019065
is_a GO:0006898 GO:0019065
part of GO:0006898 GO:0030228
part of GO:0006898 GO:0030229
is_a GO:0006898 GO:0031623
part of GO:0006898 GO:0033568

1 Synonyms

Name Type
receptor mediated endocytosis synonym