GO Term : GO:0005041 low-density lipoprotein receptor activity GO

Namespace:  molecular_function Obsolete:  false
description  Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein into the cell via endocytosis.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

1 Ontology Annotations

GO Term Gene Name
GO:0005041 IPR026296

18 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0016192 vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
GO:0006897 endocytosis A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
GO:0004872 receptor activity Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
GO:0044877 macromolecular complex binding Interacting selectively and non-covalently with any macromolecular complex.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
GO:0060089 molecular transducer activity The molecular function that accepts an input of one form and creates an output of a different form.
GO:0006898 receptor-mediated endocytosis An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
GO:0038024 cargo receptor activity Combining selectively with an extracellular substance and delivering the substance into the cell via endocytosis.
GO:0030169 low-density lipoprotein particle binding Interacting selectively and non-covalently with a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm.
GO:0005041 low-density lipoprotein receptor activity Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein into the cell via endocytosis.
GO:0030228 lipoprotein particle receptor activity Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.
GO:0071814 protein-lipid complex binding Interacting selectively and non-covalently with a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules.
GO:0071813 lipoprotein particle binding Interacting selectively and non-covalently with a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.

18 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
has_part GO:0030169 GO:0005041
is_a GO:0030228 GO:0005041
part of GO:0016192 GO:0005041
is_a GO:0060089 GO:0005041
is_a GO:0038024 GO:0005041
has_part GO:0003674 GO:0005041
has_part GO:0044877 GO:0005041
part of GO:0008150 GO:0005041
has_part GO:0005488 GO:0005041
part of GO:0006897 GO:0005041
is_a GO:0004872 GO:0005041
part of GO:0006898 GO:0005041
part of GO:0006810 GO:0005041
has_part GO:0071814 GO:0005041
part of GO:0051234 GO:0005041
part of GO:0051179 GO:0005041
has_part GO:0071813 GO:0005041
is_a GO:0003674 GO:0005041

3 Synonyms

Name Type
LDLR activity synonym
LDL receptor synonym
GO:0008032 alt_id