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GO:0008219
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cell death
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Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as "apoptotic bodies"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo. |
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GO:0006915
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apoptotic process
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A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
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GO:0043066
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negative regulation of apoptotic process
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Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. |
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GO:0042981
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regulation of apoptotic process
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Any process that modulates the occurrence or rate of cell death by apoptotic process. |
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GO:0009987
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cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0002682
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regulation of immune system process
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Any process that modulates the frequency, rate, or extent of an immune system process. |
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GO:0044763
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single-organism cellular process
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Any process that is carried out at the cellular level, occurring within a single organism. |
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GO:0044699
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single-organism process
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A biological process that involves only one organism. |
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GO:0008150
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biological_process
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Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
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GO:0065007
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biological regulation
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Any process that modulates a measurable attribute of any biological process, quality or function. |
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GO:0050794
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regulation of cellular process
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Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0050789
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regulation of biological process
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Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. |
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GO:0048523
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negative regulation of cellular process
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Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0048519
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negative regulation of biological process
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Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. |
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GO:0065008
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regulation of biological quality
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Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. |
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GO:0042592
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homeostatic process
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Any biological process involved in the maintenance of an internal steady state. |
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GO:0002376
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immune system process
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Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. |
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GO:0001776
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leukocyte homeostasis
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The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus. |
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GO:0048872
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homeostasis of number of cells
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Any biological process involved in the maintenance of the steady-state number of cells within a population of cells. |
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GO:0002260
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lymphocyte homeostasis
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The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. |
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GO:0071887
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leukocyte apoptotic process
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Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. |
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GO:0016265
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death
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A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. |
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GO:0097285
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cell-type specific apoptotic process
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Any apoptotic process in a specific cell type. |
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GO:0012501
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programmed cell death
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A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. |
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GO:0001782
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B cell homeostasis
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The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. |
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GO:0070227
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lymphocyte apoptotic process
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Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. |
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GO:0001783
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B cell apoptotic process
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Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. |
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GO:0002683
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negative regulation of immune system process
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Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. |
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GO:0010941
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regulation of cell death
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Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. |
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GO:0060548
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negative regulation of cell death
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Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. |
