GO Term : GO:0006915 apoptotic process GO

Namespace:  biological_process Obsolete:  false
description  A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

10158 Ontology Annotations

Class GO Term Gene Name Db
GOAnnotation GO:0006915 30131.t000106  
OntologyAnnotation GO:0006915 30131.m006955 GO
OntologyAnnotation GO:0006915 Lus10031429 GO
GOAnnotation GO:0006915 Lus10031429.g  
OntologyAnnotation GO:0006915 Potri.005G192900.1 GO
GOAnnotation GO:0006915 Potri.005G192900  
GOAnnotation GO:0006915 MicpuC2.EuGene.0000050398  
OntologyAnnotation GO:0006915 58093 GO
OntologyAnnotation GO:0006915 113599 GO
GOAnnotation GO:0006915 DRO_EuGene.0400010453  
GOAnnotation GO:0006915 Araha.14910s0002  
OntologyAnnotation GO:0006915 Araha.14910s0002.1.p GO
GOAnnotation GO:0006915 Araha.18318s0001  
OntologyAnnotation GO:0006915 Araha.18318s0001.1.p GO
GOAnnotation GO:0006915 Araha.3864s0008  
OntologyAnnotation GO:0006915 Araha.3864s0008.1.p GO
GOAnnotation GO:0006915 Araha.4788s0001  
OntologyAnnotation GO:0006915 Araha.4788s0001.1.p GO
GOAnnotation GO:0006915 Araha.6152s0005  
OntologyAnnotation GO:0006915 Araha.6152s0005.1.p GO
GOAnnotation GO:0006915 Cagra.1013s0016  
OntologyAnnotation GO:0006915 Cagra.1013s0017.1.p GO
GOAnnotation GO:0006915 Cagra.1013s0017  
OntologyAnnotation GO:0006915 Cagra.1013s0016.1.p GO
OntologyAnnotation GO:0006915 Cagra.1043s0032.1.p GO
GOAnnotation GO:0006915 Cagra.1043s0032  
OntologyAnnotation GO:0006915 Cagra.1065s0002.1.p GO
GOAnnotation GO:0006915 Cagra.1065s0002  
GOAnnotation GO:0006915 Cagra.10702s0003  
OntologyAnnotation GO:0006915 Cagra.10702s0003.1.p GO

8 Parents

Identifier Name Description
GO:0008219 cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as "apoptotic bodies"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo.
GO:0006915 apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0016265 death A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism.
GO:0012501 programmed cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.

596 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0006915 GO:0001781
is_a GO:0006915 GO:0001783
part of GO:0006915 GO:0001836
part of GO:0006915 GO:0001844
is_a GO:0006915 GO:0002342
is_a GO:0006915 GO:0002454
is_a GO:0006915 GO:0002516
regulates GO:0006915 GO:0002867
negatively regulates GO:0006915 GO:0002868
regulates GO:0006915 GO:0002868
regulates GO:0006915 GO:0002869
positively regulates GO:0006915 GO:0002869
regulates GO:0006915 GO:0002898
regulates GO:0006915 GO:0002899
negatively regulates GO:0006915 GO:0002899
positively regulates GO:0006915 GO:0002900
regulates GO:0006915 GO:0002900
is_a GO:0006915 GO:0002901
regulates GO:0006915 GO:0002902
negatively regulates GO:0006915 GO:0002903
regulates GO:0006915 GO:0002903
positively regulates GO:0006915 GO:0002904
regulates GO:0006915 GO:0002904
regulates GO:0006915 GO:0002905
negatively regulates GO:0006915 GO:0002906
regulates GO:0006915 GO:0002906
positively regulates GO:0006915 GO:0002907
regulates GO:0006915 GO:0002907
regulates GO:0006915 GO:0002908
negatively regulates GO:0006915 GO:0002909

17 Synonyms

Name Type
GO:0008632 alt_id
GO:0006917 alt_id
apoptosis activator activity synonym
activation of apoptosis synonym
apoptotic cell death synonym
apoptosis signaling synonym
apoptosis synonym
apoptotic programmed cell death synonym
apoptotic program synonym
cellular suicide synonym
cell suicide synonym
induction of apoptosis synonym
commitment to apoptosis synonym
programmed cell death by apoptosis synonym
induction of apoptosis by p53 synonym
type I programmed cell death synonym
signaling (initiator) caspase activity synonym