GO Term : GO:0003933 GTP cyclohydrolase activity GO

Namespace:  molecular_function Obsolete:  false
description  Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

3 Ontology Annotations

GO Term Gene Name
GO:0003933 IPR003801
GO:0003933 IPR007839
GO:0003933 IPR022840

9 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0019238 cyclohydrolase activity Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring.
GO:0003933 GTP cyclohydrolase activity Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.

18 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0019238 GO:0003933
is_a GO:0016814 GO:0003933
is_a GO:0003824 GO:0003933
is_a GO:0003674 GO:0003933
part of GO:0008150 GO:0003933
is_a GO:0016787 GO:0003933
part of GO:0008152 GO:0003933
is_a GO:0016810 GO:0003933
is_a GO:0003933 GO:0003934
is_a GO:0003933 GO:0003935
regulates GO:0003933 GO:0043095
regulates GO:0003933 GO:0043104
positively regulates GO:0003933 GO:0043104
negatively regulates GO:0003933 GO:0043105
regulates GO:0003933 GO:0043105
is_a GO:0003933 GO:0043740
is_a GO:0003933 GO:0044682
regulates GO:0003933 GO:0060308

0 Synonyms