GO Term : GO:0005087 Ran guanyl-nucleotide exchange factor activity GO
Namespace:  molecular_function Obsolete:  false
description  Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ran family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

38 Parents

Identifier Name Description
GO:0000166 nucleotide binding Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0043087 regulation of GTPase activity Any process that modulates the rate of GTP hydrolysis by a GTPase.
GO:0019001 guanyl nucleotide binding Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate.
GO:0032549 ribonucleoside binding Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.
GO:0001882 nucleoside binding Interacting selectively and non-covalently with a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose.
GO:0043085 positive regulation of catalytic activity Any process that activates or increases the activity of an enzyme.
GO:0017076 purine nucleotide binding Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0005085 guanyl-nucleotide exchange factor activity Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
GO:0036094 small molecule binding Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule.
GO:0043167 ion binding Interacting selectively and non-covalently with ions, charged atoms or groups of atoms.
GO:0097367 carbohydrate derivative binding Interacting selectively and non-covalently with a carbohydrate derivative.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:1901363 heterocyclic compound binding Interacting selectively and non-covalently with heterocyclic compound.
GO:0097159 organic cyclic compound binding Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.
GO:0043168 anion binding Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net negative charge.
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:1901265 nucleoside phosphate binding Interacting selectively and non-covalently with nucleoside phosphate.
GO:0048518 positive regulation of biological process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0044093 positive regulation of molecular function Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
GO:0098772 molecular function regulator A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators.
GO:0001883 purine nucleoside binding Interacting selectively and non-covalently with a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose.
GO:0032553 ribonucleotide binding Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
GO:0032555 purine ribonucleotide binding Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.

39 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0005088 GO:0005087
part of GO:0043085 GO:0005087
negatively regulates GO:0032561 GO:0005087
part of GO:0051345 GO:0005087
part of GO:0044093 GO:0005087
negatively regulates GO:0019003 GO:0005087
part of GO:0043087 GO:0005087
negatively regulates GO:0097159 GO:0005087
part of GO:0009893 GO:0005087
is_a GO:0098772 GO:0005087
negatively regulates GO:0032549 GO:0005087
part of GO:0065007 GO:0005087
negatively regulates GO:0017076 GO:0005087
part of GO:0065009 GO:0005087
negatively regulates GO:0003674 GO:0005087
negatively regulates GO:0036094 GO:0005087
negatively regulates GO:0000166 GO:0005087
negatively regulates GO:1901363 GO:0005087
negatively regulates GO:1901265 GO:0005087
is_a GO:0005085 GO:0005087
part of GO:0050789 GO:0005087
negatively regulates GO:0032550 GO:0005087
part of GO:0019222 GO:0005087
part of GO:0051336 GO:0005087
negatively regulates GO:0032553 GO:0005087
part of GO:0008150 GO:0005087
negatively regulates GO:0032555 GO:0005087
negatively regulates GO:0019001 GO:0005087
part of GO:0043547 GO:0005087
negatively regulates GO:0097367 GO:0005087

1 Synonyms

Name Type
RCC1 synonym