GO Term : GO:0006924 activation-induced cell death of T cells GO

Namespace:  biological_process Obsolete:  false
description  A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

21 Parents

Identifier Name Description
GO:0008219 cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as "apoptotic bodies"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo.
GO:0006915 apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0065008 regulation of biological quality Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
GO:0042592 homeostatic process Any biological process involved in the maintenance of an internal steady state.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0001776 leukocyte homeostasis The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.
GO:0043029 T cell homeostasis The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0002260 lymphocyte homeostasis The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.
GO:0071887 leukocyte apoptotic process Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
GO:0016265 death A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism.
GO:0097285 cell-type specific apoptotic process Any apoptotic process in a specific cell type.
GO:0012501 programmed cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GO:0070227 lymphocyte apoptotic process Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
GO:0070231 T cell apoptotic process Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
GO:0006924 activation-induced cell death of T cells A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.

29 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0070231 GO:0006924
part of GO:0043029 GO:0006924
part of GO:0002260 GO:0006924
is_a GO:0044763 GO:0006924
is_a GO:0070227 GO:0006924
is_a GO:0071887 GO:0006924
is_a GO:0044699 GO:0006924
is_a GO:0006915 GO:0006924
is_a GO:0016265 GO:0006924
is_a GO:0008219 GO:0006924
is_a GO:0097285 GO:0006924
is_a GO:0009987 GO:0006924
part of GO:0042592 GO:0006924
part of GO:0001776 GO:0006924
part of GO:0065008 GO:0006924
part of GO:0048872 GO:0006924
part of GO:0065007 GO:0006924
part of GO:0008150 GO:0006924
part of GO:0002376 GO:0006924
is_a GO:0008150 GO:0006924
is_a GO:0012501 GO:0006924
regulates GO:0006924 GO:0070235
regulates GO:0006924 GO:0070235
negatively regulates GO:0006924 GO:0070236
negatively regulates GO:0006924 GO:0070236
regulates GO:0006924 GO:0070236
positively regulates GO:0006924 GO:0070237
positively regulates GO:0006924 GO:0070237
regulates GO:0006924 GO:0070237

6 Synonyms

Name Type
activated T cell apoptosis synonym
antigen-driven apoptosis synonym
AICD synonym
activation-induced cell death of T lymphocytes synonym
activation-induced cell death of T-lymphocytes synonym
activation-induced cell death of T-cells synonym