GO Term : GO:0030057 desmosome GO

Namespace:  cellular_component Obsolete:  false
description  A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.

0 Cross References

1 Data Sets

Name URL
InterPro domain GO annotations  

1 Ontology

Name
GO

2 Ontology Annotations

GO Term Gene Name
GO:0030057 IPR028432
GO:0030057 IPR028434

5 Parents

Identifier Name Description
GO:0030054 cell junction A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005911 cell-cell junction A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
GO:0070161 anchoring junction A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.
GO:0030057 desmosome A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0005911 GO:0030057
is_a GO:0070161 GO:0030057
is_a GO:0005575 GO:0030057
is_a GO:0030054 GO:0030057
part of GO:0030057 GO:0090635
part of GO:0030057 GO:0090636
part of GO:0030057 GO:0090637

2 Synonyms

Name Type
spot desmosome synonym
macula adherens synonym