GO Term : GO:0090636 outer dense plaque of desmosome GO

Namespace:  cellular_component Obsolete:  false
description  The desmosomal part containing plakoglobins, plakophilins, the N-termini of desmoplakins, as well as the cytoplasmic tails of the desmosomal cadherins, which together attach the plaque to the plasma membrane.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

8 Parents

Identifier Name Description
GO:0030054 cell junction A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0005911 cell-cell junction A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
GO:0070161 anchoring junction A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.
GO:0030057 desmosome A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.
GO:0090636 outer dense plaque of desmosome The desmosomal part containing plakoglobins, plakophilins, the N-termini of desmoplakins, as well as the cytoplasmic tails of the desmosomal cadherins, which together attach the plaque to the plasma membrane.

8 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0030057 GO:0090636
is_a GO:0044464 GO:0090636
part of GO:0005575 GO:0090636
is_a GO:0005575 GO:0090636
part of GO:0030054 GO:0090636
part of GO:0005911 GO:0090636
part of GO:0070161 GO:0090636
part of GO:0005623 GO:0090636

0 Synonyms