GO Term : GO:0030264 nuclear fragmentation involved in apoptotic nuclear change GO

Namespace:  biological_process Obsolete:  false
description  The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

22 Parents

Identifier Name Description
GO:0008219 cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as "apoptotic bodies"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo.
GO:0006915 apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0061024 membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0006997 nucleus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
GO:0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0022411 cellular component disassembly A cellular process that results in the breakdown of a cellular component.
GO:0044802 single-organism membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane, involving only one organism.
GO:0010256 endomembrane system organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.
GO:0016265 death A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism.
GO:0012501 programmed cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GO:0030262 apoptotic nuclear changes Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.
GO:0097194 execution phase of apoptosis A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0006921 cellular component disassembly involved in execution phase of apoptosis The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis.
GO:0006998 nuclear envelope organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.
GO:0071763 nuclear membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane.
GO:0030264 nuclear fragmentation involved in apoptotic nuclear change The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA.

31 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0071763 GO:0030264
part of GO:0030262 GO:0030264
is_a GO:0071763 GO:0030264
part of GO:0030262 GO:0030264
part of GO:0006915 GO:0030264
part of GO:0044699 GO:0030264
part of GO:0016265 GO:0030264
is_a GO:0044699 GO:0030264
part of GO:0016043 GO:0030264
part of GO:0006996 GO:0030264
part of GO:0006997 GO:0030264
part of GO:0009987 GO:0030264
part of GO:0006998 GO:0030264
part of GO:0008219 GO:0030264
part of GO:0010256 GO:0030264
part of GO:0061024 GO:0030264
is_a GO:0016043 GO:0030264
is_a GO:0071840 GO:0030264
is_a GO:0061024 GO:0030264
is_a GO:0044802 GO:0030264
part of GO:0071840 GO:0030264
part of GO:0022411 GO:0030264
part of GO:0044763 GO:0030264
is_a GO:0008150 GO:0030264
part of GO:0097194 GO:0030264
is_a GO:0009987 GO:0030264
part of GO:0006921 GO:0030264
part of GO:0044802 GO:0030264
is_a GO:0044763 GO:0030264
part of GO:0012501 GO:0030264

3 Synonyms

Name Type
apoptotic nuclear fragmentation synonym
nuclear fragmentation during apoptosis synonym
nucleus fragmentation synonym