GO Term : GO:0031091 platelet alpha granule GO

Namespace:  cellular_component Obsolete:  false
description  A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

18 Parents

Identifier Name Description
GO:0005737 cytoplasm All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0005622 intracellular The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0043231 intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0016023 cytoplasmic membrane-bounded vesicle A membrane-bounded vesicle found in the cytoplasm of the cell.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0044444 cytoplasmic part Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0044424 intracellular part Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0043227 membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
GO:0043226 organelle Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
GO:0043229 intracellular organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0012505 endomembrane system A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
GO:0031410 cytoplasmic vesicle A vesicle formed of membrane or protein, found in the cytoplasm of a cell.
GO:0031982 vesicle Any small, fluid-filled, spherical organelle enclosed by membrane or protein.
GO:0031988 membrane-bounded vesicle Any small, fluid-filled, spherical organelle enclosed by a lipid bilayer.
GO:0030141 secretory granule A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
GO:0031091 platelet alpha granule A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).

22 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0030141 GO:0031091
is_a GO:0005575 GO:0031091
is_a GO:0031410 GO:0031091
is_a GO:0031982 GO:0031091
is_a GO:0043229 GO:0031091
is_a GO:0044424 GO:0031091
is_a GO:0016023 GO:0031091
is_a GO:0043226 GO:0031091
part of GO:0005622 GO:0031091
is_a GO:0043227 GO:0031091
part of GO:0005623 GO:0031091
is_a GO:0044464 GO:0031091
is_a GO:0044444 GO:0031091
part of GO:0012505 GO:0031091
part of GO:0005737 GO:0031091
part of GO:0044464 GO:0031091
is_a GO:0043231 GO:0031091
is_a GO:0031988 GO:0031091
part of GO:0044424 GO:0031091
part of GO:0005575 GO:0031091
part of GO:0031091 GO:0031092
part of GO:0031091 GO:0031093

1 Synonyms

Name Type
platelet alpha-granule synonym