GO Term : GO:1900137 negative regulation of chemokine activity GO

Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

62 Parents

Identifier Name Description
GO:0005515 protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0048870 cell motility Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
GO:0006935 chemotaxis The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
GO:0005102 receptor binding Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0008009 chemokine activity The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0006928 movement of cell or subcellular component The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.
GO:0005125 cytokine activity Functions to control the survival, growth, differentiation and effector function of tissues and cells.
GO:0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of cell migration.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050920 regulation of chemotaxis Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:0044092 negative regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GO:0070887 cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GO:0009605 response to external stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.

93 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:1900137 GO:0039553
is_a GO:0060302 GO:1900137
is_a GO:0050922 GO:1900137
negatively regulates GO:0008009 GO:1900137
is_a GO:0030336 GO:1900137
negatively regulates GO:0008009 GO:1900137
is_a GO:0065007 GO:1900137
is_a GO:1900136 GO:1900137
is_a GO:0008150 GO:1900137
is_a GO:0032101 GO:1900137
is_a GO:0032102 GO:1900137
negatively regulates GO:0070887 GO:1900137
is_a GO:0051100 GO:1900137
negatively regulates GO:0051179 GO:1900137
regulates GO:0016477 GO:1900137
negatively regulates GO:0001664 GO:1900137
negatively regulates GO:0048870 GO:1900137
is_a GO:0043393 GO:1900137
negatively regulates GO:0042330 GO:1900137
negatively regulates GO:0009987 GO:1900137
negatively regulates GO:0005102 GO:1900137
regulates GO:0008009 GO:1900137
negatively regulates GO:0060326 GO:1900137
negatively regulates GO:0042379 GO:1900137
is_a GO:0048521 GO:1900137
regulates GO:0003674 GO:1900137
is_a GO:0048523 GO:1900137
is_a GO:0032091 GO:1900137
is_a GO:0048519 GO:1900137
is_a GO:2000145 GO:1900137

4 Synonyms

Name Type
down-regulation of chemokine activity synonym
down regulation of chemokine activity synonym
inhibition of chemokine activity synonym
downregulation of chemokine activity synonym