GO Term : GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization GO

Namespace:  biological_process Obsolete:  false
description  The macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

33 Parents

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0006914 autophagy The process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0000045 autophagosome assembly The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
GO:0007005 mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
GO:0007033 vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0000422 mitophagy The autophagic process in which mitochondria are delivered to the vacuole and degraded in response to changing cellular conditions.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:1902589 single-organism organelle organization An organelle organization which involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0033554 cellular response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0044248 cellular catabolic process The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
GO:0044712 single-organism catabolic process A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves a single organism.
GO:0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
GO:0070925 organelle assembly The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0022607 cellular component assembly The aggregation, arrangement and bonding together of a cellular component.
GO:0016236 macroautophagy The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Though once thought to be a purely non-selective process, it appears that some types of macroautophagy, e.g. macropexophagy, macromitophagy, may involve selective targeting of the targets to be degraded.
GO:0022411 cellular component disassembly A cellular process that results in the breakdown of a cellular component.
GO:0061726 mitochondrion disassembly The disaggregation of a mitochondrion into its constituent components.
GO:1903008 organelle disassembly The disaggregation of an organelle into its constituent components.
GO:0000423 macromitophagy Degradation of a mitochondrion by macroautophagy.

41 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0098779 GO:0061734
is_a GO:0016236 GO:0061734
is_a GO:0061726 GO:0061734
is_a GO:0009987 GO:0061734
part of GO:0051716 GO:0061734
is_a GO:0071840 GO:0061734
has_part GO:0008152 GO:0061734
has_part GO:0008150 GO:0061734
is_a GO:0006914 GO:0061734
has_part GO:0071840 GO:0061734
has_part GO:0000045 GO:0061734
has_part GO:0044248 GO:0061734
is_a GO:0006996 GO:0061734
is_a GO:0044710 GO:0061734
is_a GO:0007005 GO:0061734
is_a GO:0044699 GO:0061734
is_a GO:1902589 GO:0061734
has_part GO:0016043 GO:0061734
is_a GO:0008150 GO:0061734
part of GO:0098780 GO:0061734
is_a GO:0008152 GO:0061734
has_part GO:0007033 GO:0061734
is_a GO:0009056 GO:0061734
part of GO:0050896 GO:0061734
has_part GO:0009056 GO:0061734
is_a GO:0044712 GO:0061734
part of GO:0033554 GO:0061734
has_part GO:0070925 GO:0061734
is_a GO:0016043 GO:0061734
is_a GO:0000422 GO:0061734

0 Synonyms