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GO:0008152
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metabolic process
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The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. |
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GO:0006412
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translation
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The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
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GO:0009058
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biosynthetic process
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The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. |
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GO:0044237
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cellular metabolic process
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The chemical reactions and pathways by which individual cells transform chemical substances. |
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GO:0006413
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translational initiation
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The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. |
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GO:0006807
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nitrogen compound metabolic process
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The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium. |
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GO:0019538
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protein metabolic process
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The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification. |
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GO:0010468
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regulation of gene expression
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Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. |
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GO:0071704
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organic substance metabolic process
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The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. |
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GO:0007005
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mitochondrion organization
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. |
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GO:0044238
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primary metabolic process
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The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
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GO:0043043
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peptide biosynthetic process
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The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. |
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GO:0044249
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cellular biosynthetic process
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The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. |
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GO:0017148
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negative regulation of translation
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Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA. |
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GO:0009059
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macromolecule biosynthetic process
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The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. |
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GO:0044260
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cellular macromolecule metabolic process
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The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. |
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GO:0009890
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negative regulation of biosynthetic process
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Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. |
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GO:0006446
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regulation of translational initiation
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Any process that modulates the frequency, rate or extent of translational initiation. |
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GO:0006518
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peptide metabolic process
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The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. |
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GO:0016043
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cellular component organization
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A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. |
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GO:0044267
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cellular protein metabolic process
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The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification. |
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GO:0009987
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cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0045947
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negative regulation of translational initiation
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Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation. |
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GO:0006417
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regulation of translation
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Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA. |
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GO:0006996
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organelle organization
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A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
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GO:0032543
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mitochondrial translation
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The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. |
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GO:0044763
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single-organism cellular process
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Any process that is carried out at the cellular level, occurring within a single organism. |
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GO:0044699
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single-organism process
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A biological process that involves only one organism. |
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GO:0071840
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cellular component organization or biogenesis
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A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. |
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GO:1902589
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single-organism organelle organization
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An organelle organization which involves only one organism. |
