GO Term : GO:0075108 negative regulation by symbiont of host adenylate cyclase activity GO
Namespace:  biological_process Obsolete:  false
description  Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

131 Parents

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0016829 lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0006796 phosphate-containing compound metabolic process The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0006139 nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0006164 purine nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0009165 nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0009117 nucleotide metabolic process The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
GO:0006725 cellular aromatic compound metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
GO:0009152 purine ribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0009190 cyclic nucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
GO:0016849 phosphorus-oxygen lyase activity Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
GO:0006163 purine nucleotide metabolic process The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
GO:1901137 carbohydrate derivative biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0043086 negative regulation of catalytic activity Any process that stops or reduces the activity of an enzyme.
GO:0045980 negative regulation of nucleotide metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
GO:0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0055086 nucleobase-containing small molecule metabolic process The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
GO:0006793 phosphorus metabolic process The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
GO:0045936 negative regulation of phosphate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
GO:0004016 adenylate cyclase activity Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
GO:0006171 cAMP biosynthetic process The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).

193 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:0052053 GO:0075108
is_a GO:0075106 GO:0075108
is_a GO:0007194 GO:0075108
is_a GO:0048523 GO:0075108
regulates GO:0018130 GO:0075108
negatively regulates GO:0009190 GO:0075108
regulates GO:0009260 GO:0075108
is_a GO:0030799 GO:0075108
is_a GO:0051817 GO:0075108
negatively regulates GO:0044238 GO:0075108
negatively regulates GO:0044237 GO:0075108
regulates GO:0003674 GO:0075108
negatively regulates GO:1901137 GO:0075108
negatively regulates GO:1901135 GO:0075108
negatively regulates GO:0016849 GO:0075108
regulates GO:1901566 GO:0075108
is_a GO:1900371 GO:0075108
is_a GO:1900372 GO:0075108
regulates GO:1901564 GO:0075108
negatively regulates GO:0009117 GO:0075108
negatively regulates GO:0090407 GO:0075108
is_a GO:0052199 GO:0075108
negatively regulates GO:0019438 GO:0075108
is_a GO:0048519 GO:0075108
negatively regulates GO:0006807 GO:0075108
is_a GO:0043086 GO:0075108
regulates GO:0003824 GO:0075108
regulates GO:0009150 GO:0075108
regulates GO:0009152 GO:0075108
negatively regulates GO:0044249 GO:0075108

8 Synonyms

Name Type
Negative regulation by symbiont of host 3',5'-cyclic AMP synthetase activity synonym
Negative regulation by symbiont of host adenylyl cyclase activity synonym
Negative regulation by symbiont of host adenyl cyclase activity synonym
Negative regulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity synonym
Negative regulation by symbiont of host adenylylcyclase activity synonym
Negative regulation by symbiont of host ATP pyrophosphate-lyase activity synonym
Negative regulation by symbiont of host ATP diphosphate-lyase (cyclizing) activity synonym
Negative regulation by symbiont of host cAMP generating peptide activity synonym