GO Term : GO:0097352 autophagosome maturation GO

Namespace:  biological_process Obsolete:  false
description  The process in which autophagosomes, double-membraned vacuoles containing cytoplasmic material fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

21 Parents

Identifier Name Description
GO:0006914 autophagy The process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
GO:0007033 vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
GO:0061024 membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:1902589 single-organism organelle organization An organelle organization which involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0016236 macroautophagy The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Though once thought to be a purely non-selective process, it appears that some types of macroautophagy, e.g. macropexophagy, macromitophagy, may involve selective targeting of the targets to be degraded.
GO:0044802 single-organism membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane, involving only one organism.
GO:0090174 organelle membrane fusion The joining of two lipid bilayers to form a single organelle membrane.
GO:0044801 single-organism membrane fusion The membrane organization process that joins two lipid bilayers to form a single membrane, involving only one organism.
GO:0061025 membrane fusion The membrane organization process that joins two lipid bilayers to form a single membrane.
GO:0048284 organelle fusion The creation of a single organelle from two or more organelles.
GO:0022406 membrane docking The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.
GO:0016240 autophagosome docking The initial attachment of an autophagosome membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.
GO:0097576 vacuole fusion Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.
GO:0097352 autophagosome maturation The process in which autophagosomes, double-membraned vacuoles containing cytoplasmic material fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.

34 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
has_part GO:0016240 GO:0097352
is_a GO:0097576 GO:0097352
part of GO:0016236 GO:0097352
is_a GO:0090174 GO:0097352
is_a GO:1902589 GO:0097352
has_part GO:0022406 GO:0097352
part of GO:0009987 GO:0097352
is_a GO:0044763 GO:0097352
has_part GO:0044699 GO:0097352
is_a GO:0016043 GO:0097352
has_part GO:0044763 GO:0097352
is_a GO:0044801 GO:0097352
is_a GO:0071840 GO:0097352
part of GO:0006914 GO:0097352
is_a GO:0044699 GO:0097352
is_a GO:0044802 GO:0097352
has_part GO:0008150 GO:0097352
is_a GO:0009987 GO:0097352
is_a GO:0006996 GO:0097352
part of GO:0008150 GO:0097352
is_a GO:0061025 GO:0097352
is_a GO:0007033 GO:0097352
is_a GO:0061024 GO:0097352
has_part GO:0009987 GO:0097352
is_a GO:0048284 GO:0097352
is_a GO:0008150 GO:0097352
regulates GO:0097352 GO:1901096
regulates GO:0097352 GO:1901096
negatively regulates GO:0097352 GO:1901097
negatively regulates GO:0097352 GO:1901097

7 Synonyms

Name Type
autolysosome formation synonym
amphisome-lysosome fusion synonym
autophagic vacuole maturation synonym
autophagic vacuole fusion synonym
fusion of autophagosome with lysosome synonym
autophagosome fusion synonym
GO:0000046 alt_id