GO:0006355
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regulation of transcription, DNA-templated
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Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
GO:0006508
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proteolysis
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The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
GO:0006357
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regulation of transcription from RNA polymerase II promoter
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Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
GO:0030163
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protein catabolic process
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The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. |
GO:0007165
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signal transduction
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The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
GO:0008152
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metabolic process
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The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. |
GO:0044237
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cellular metabolic process
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The chemical reactions and pathways by which individual cells transform chemical substances. |
GO:0051603
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proteolysis involved in cellular protein catabolic process
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The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells. |
GO:0006950
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response to stress
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Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). |
GO:0006511
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ubiquitin-dependent protein catabolic process
|
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein. |
GO:0019538
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protein metabolic process
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The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification. |
GO:0010468
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regulation of gene expression
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Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. |
GO:0043161
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proteasome-mediated ubiquitin-dependent protein catabolic process
|
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. |
GO:0071704
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organic substance metabolic process
|
The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. |
GO:0051252
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regulation of RNA metabolic process
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Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. |
GO:0044238
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primary metabolic process
|
The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. |
GO:0045893
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positive regulation of transcription, DNA-templated
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Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
GO:0051716
|
cellular response to stimulus
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Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. |
GO:0044260
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cellular macromolecule metabolic process
|
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. |
GO:0007154
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cell communication
|
Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. |
GO:0044267
|
cellular protein metabolic process
|
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification. |
GO:0009987
|
cellular process
|
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
GO:0045944
|
positive regulation of transcription from RNA polymerase II promoter
|
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
GO:0044763
|
single-organism cellular process
|
Any process that is carried out at the cellular level, occurring within a single organism. |
GO:0044699
|
single-organism process
|
A biological process that involves only one organism. |
GO:0008150
|
biological_process
|
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
GO:0050896
|
response to stimulus
|
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. |
GO:0033554
|
cellular response to stress
|
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). |
GO:0043170
|
macromolecule metabolic process
|
The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. |
GO:0065007
|
biological regulation
|
Any process that modulates a measurable attribute of any biological process, quality or function. |