GO Term : GO:1903073 negative regulation of death-inducing signaling complex assembly GO
Namespace:  biological_process Obsolete:  false
description  Any process that stops, prevents or reduces the frequency, rate or extent of death-inducing signaling complex assembly.
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0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

57 Parents

Identifier Name Description
GO:0007165 signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0007166 cell surface receptor signaling pathway A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
GO:0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of signal transduction.
GO:0006461 protein complex assembly The aggregation, arrangement and bonding together of a set of components to form a protein complex.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0008219 cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as "apoptotic bodies"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo.
GO:0006915 apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0043066 negative regulation of apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
GO:0042981 regulation of apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process.
GO:0007154 cell communication Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0065003 macromolecular complex assembly The aggregation, arrangement and bonding together of a set of macromolecules to form a complex.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0071822 protein complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.
GO:0043933 macromolecular complex subunit organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a macromolecular complex.
GO:0022607 cellular component assembly The aggregation, arrangement and bonding together of a cellular component.
GO:0044085 cellular component biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.
GO:0070271 protein complex biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of non-protein components, and those protein modifications that are involved in synthesis or assembly of the complex.
GO:0048523 negative regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0023052 signaling The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
GO:0044700 single organism signaling A signaling process occurring within a single organism.

92 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
is_a GO:1903072 GO:1903073
is_a GO:2001237 GO:1903073
negatively regulates GO:0071550 GO:1903073
is_a GO:0031333 GO:1903073
negatively regulates GO:0071550 GO:1903073
is_a GO:0065007 GO:1903073
is_a GO:0010648 GO:1903073
regulates GO:0044085 GO:1903073
is_a GO:0060548 GO:1903073
is_a GO:2001236 GO:1903073
negatively regulates GO:0050896 GO:1903073
is_a GO:2001234 GO:1903073
is_a GO:2001233 GO:1903073
regulates GO:0044763 GO:1903073
is_a GO:0043254 GO:1903073
is_a GO:0050789 GO:1903073
is_a GO:0048585 GO:1903073
negatively regulates GO:0008150 GO:1903073
is_a GO:0010646 GO:1903073
is_a GO:0048583 GO:1903073
negatively regulates GO:0071822 GO:1903073
negatively regulates GO:0016265 GO:1903073
negatively regulates GO:0044763 GO:1903073
regulates GO:0006915 GO:1903073
regulates GO:0022607 GO:1903073
is_a GO:0009968 GO:1903073
is_a GO:0023051 GO:1903073
negatively regulates GO:0070271 GO:1903073
regulates GO:0050794 GO:1903073
is_a GO:0009966 GO:1903073

39 Synonyms

Name Type
down regulation of death-inducing signalling complex assembly synonym
down regulation of death-inducing signaling complex formation synonym
down regulation of DISC formation synonym
down regulation of DISC assembly synonym
down-regulation of death domain-mediated complex assembly synonym
down-regulation of DD-mediated complex assembly synonym
down-regulation of death-inducing signaling complex assembly synonym
down-regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway synonym
down-regulation of death-inducing signalling complex assembly synonym
down-regulation of death-inducing signaling complex formation synonym
down-regulation of DISC formation synonym
down-regulation of DISC assembly synonym
downregulation of death domain-mediated complex assembly synonym
downregulation of DD-mediated complex assembly synonym
downregulation of death-inducing signaling complex assembly synonym
downregulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway synonym
downregulation of death-inducing signalling complex assembly synonym
downregulation of death-inducing signaling complex formation synonym
downregulation of DISC formation synonym
downregulation of DISC assembly synonym
inhibition of death domain-mediated complex assembly synonym
inhibition of DD-mediated complex assembly synonym
inhibition of death-inducing signaling complex assembly synonym
inhibition of death domain-mediated complex assembly involved in extrinsic apoptotic pathway synonym
inhibition of death-inducing signalling complex assembly synonym
inhibition of death-inducing signaling complex formation synonym
inhibition of DISC formation synonym
inhibition of DISC assembly synonym
negative regulation of death domain-mediated complex assembly synonym
negative regulation of DD-mediated complex assembly synonym