Type: | Family | Name: | Vacuolar protein sorting-associated protein 11 |
Description: | This entry includes E3 ubiquitin-protein ligase Pep5 (also known as vacuolar protein sorting-associated protein 11, Vps11) from fungi, and its homologues from plants and animals. Pep5 is a peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis []. It is also identified as an E3 ubiquitin ligase that regulates histone protein levels in Saccharomyces cerevisiae []. Human Vps11 may play a role in vesicle-mediated protein trafficking []. | Short Name: | VPS11 |