Protein Domain : IPR000659

Type:  Family Name:  Pyridoxamine 5'-phosphate oxidase
Description:  Pyridoxamine 5'-phosphate oxidase () is an enzyme that is involved in the de novo synthesis of pyridoxine (vitamin B6) and pyridoxal phosphate. It oxidizes pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P. The enzyme requires the presence of flavin mononucleotide (FMN) as a cofactor, although there is some evidence that coenzyme F420 may perform this role in some species [].The sequences of the enzyme from bacterial (genes pdxH or fprA) [] andfungal (gene PDX3) [] sources show that this protein has been highly conserved throughout evolution. PdxH is evolutionary related [] to one of the enzymes in the phenazine biosynthesis protein pathway, phzD (also known as phzG). Short Name:  Pyridox_Oxase
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0 Child Features

4 Contains

DB identifier Type Name
IPR011576 Domain Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain
IPR019576 Domain Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal
IPR012349 Domain FMN-binding split barrel
IPR019740 Conserved_site Pyridoxamine 5'-phosphate oxidase, conserved site

4 Cross Referencess

Identifier
PTHR10851
PIRSF000190
TIGR00558
MF_01629

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004733 IPR000659
GO:0008615 IPR000659
GO:0055114 IPR000659

3 Ontology Annotations

GO Term Gene Name
GO:0004733 IPR000659
GO:0008615 IPR000659
GO:0055114 IPR000659

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
81184 D8R082 PAC:15406031 Selaginella moellendorffii 447  
270695 D8RAV7 PAC:15421852 Selaginella moellendorffii 192  
evm.model.supercontig_36.204 PAC:16418398 Carica papaya 461  
evm.model.supercontig_96.56 PAC:16428998 Carica papaya 198  
29908.m006117 B9RJT5 PAC:16812937 Ricinus communis 546  
Cucsa.259350.1 PAC:16973002 Cucumis sativus 198  
Cucsa.259350.2 PAC:16973003 Cucumis sativus 166  
Cucsa.311770.1 A0A0A0LEN5 PAC:16976749 Cucumis sativus 530  
orange1.1g033147m A0A067HF71 PAC:18137530 Citrus sinensis 126  
orange1.1g031333m A0A067H6H1 PAC:18137529 Citrus sinensis 161  
AT5G49970.1 Q9LTX3 PAC:19671695 Arabidopsis thaliana 530  
AT5G49970.2 Q9LTX3 PAC:19671696 Arabidopsis thaliana 466  
AT2G46580.1 Q9ZPY1 PAC:19641051 Arabidopsis thaliana 198  
Thhalv10013217m V4LIW1 PAC:20204053 Eutrema salsugineum 533  
Thhalv10001639m V4L6L7 PAC:20188805 Eutrema salsugineum 200  
Ciclev10000790m V4V581 PAC:20785508 Citrus clementina 540  
Ciclev10001061m V4TBY4 PAC:20785510 Citrus clementina 467  
Ciclev10001064m V4TBY4 PAC:20785511 Citrus clementina 467  
Ciclev10000837m V4T6R1 PAC:20785509 Citrus clementina 526  
Ciclev10001362m V4T6T0 PAC:20788876 Citrus clementina 403  
Ciclev10001057m V4TBY8 PAC:20788875 Citrus clementina 467  
Ciclev10022329m V4TWV9 PAC:20807933 Citrus clementina 200  
Lus10005977 PAC:23175083 Linum usitatissimum 196  
Lus10002098 PAC:23151643 Linum usitatissimum 1176  
Lus10000833 PAC:23170689 Linum usitatissimum 961  
Potri.002G102600.2 A0A2K2BGL8 PAC:27024120 Populus trichocarpa 542  
Potri.002G102600.1 A0A2K2BGL8 PAC:27024119 Populus trichocarpa 542  
Potri.002G102600.3 PAC:27024122 Populus trichocarpa 453  
Potri.002G102600.4 A0A2K2BGL8 PAC:27024121 Populus trichocarpa 542  
Potri.002G173800.6 PAC:27022530 Populus trichocarpa 192  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8586283
            1356963
            7896706
            20675471