Protein Domain : IPR013802

Type:  Domain Name:  Formiminotransferase, C-terminal subdomain
Description:  The formiminotransferase (FT) domain of formiminotransferase-cyclodeaminase (FTCD) forms a homodimer, with each protomer being comprised of two subdomains. The formiminotransferase domain has an N-terminal subdomain that is made up of a six-stranded mixed beta-pleated sheet and five alpha helices, which are arranged on the external surface of the beta sheet. This, in turn, faces the beta-sheet of the C-terminal subdomain to form a double beta-sheet layer. The two subdomains are separated by a short linker sequence, which is not thought to be any more flexible than the remainder of the molecule. The substrate is predicted to form a number of contacts with residues found in both the N-terminal and C-terminal subdomains []. In humans, deficiency of this enzyme results in a disease phenotype [].This entry represents the C-terminal subdomain of the formiminotransferase domain. Short Name:  Formiminotransferase_C
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
PF02971
G3DSA:3.30.70.670

1 Found In

DB identifier Type Name
IPR004227 Domain Formiminotransferase catalytic domain

3 GO Annotations

GO Term Gene Name
GO:0005542 IPR013802
GO:0016740 IPR013802
GO:0008152 IPR013802

3 Ontology Annotations

GO Term Gene Name
GO:0005542 IPR013802
GO:0016740 IPR013802
GO:0008152 IPR013802

1 Parent Features

DB identifier Type Name
IPR022384 Domain Formiminotransferase subdomain

587 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
438865 D8R013 PAC:15401940 Selaginella moellendorffii 294  
29983.m003258 B9RW60 PAC:16815023 Ricinus communis 299  
29591.m000135 B9T3K5 PAC:16803339 Ricinus communis 71  
Cucsa.119520.1 A0A0A0KAE4 PAC:16960995 Cucumis sativus 324  
Cucsa.119530.1 A0A0A0KAZ4 PAC:16960996 Cucumis sativus 299  
Cucsa.119530.2 A0A0A0KAZ4 PAC:16960997 Cucumis sativus 299  
orange1.1g036475m A0A067DIP9 PAC:18116098 Citrus sinensis 684  
orange1.1g026946m A0A067DYV2 PAC:18117743 Citrus sinensis 230  
orange1.1g029879m A0A067DXR0 PAC:18117744 Citrus sinensis 186  
orange1.1g039996m A0A067DLD7 PAC:18117751 Citrus sinensis 241  
AT2G20830.3 F4IFJ9 PAC:19639785 Arabidopsis thaliana 341  
AT2G20830.2 F4IFK0 PAC:19639784 Arabidopsis thaliana 431  
AT2G20830.1 Q9SKT4 PAC:19639786 Arabidopsis thaliana 297  
Thhalv10001991m V4MDC1 PAC:20200420 Eutrema salsugineum 431  
Ciclev10001997m V4SVF9 PAC:20788669 Citrus clementina 300  
Ciclev10017445m V4TJI3 PAC:20815739 Citrus clementina 424  
Lus10018558 PAC:23180377 Linum usitatissimum 303  
Lus10018559 PAC:23180440 Linum usitatissimum 307  
Lus10039789 PAC:23165135 Linum usitatissimum 298  
Lus10039790 PAC:23165283 Linum usitatissimum 309  
Potri.013G145700.1 A0A2K1Y5P9 PAC:26994772 Populus trichocarpa 299  
Potri.013G145600.1 B9I687 PAC:26995945 Populus trichocarpa 316  
Potri.013G145600.2 A0A2K1Y5U1 PAC:26995946 Populus trichocarpa 300  
Potri.019G104700.1 A0A2K1WSE5 PAC:27026271 Populus trichocarpa 316  
Gorai.005G205100.1 A0A0D2PWH9 PAC:26802457 Gossypium raimondii 468  
14777 I0YZZ2 PAC:27391106 Coccomyxa subellipsoidea C-169 301  
151974 C1MPD0 PAC:27347566 Micromonas pusilla CCMP1545 337  
80383 C1E2A7 PAC:27397941 Micromonas sp RCC299 330  
88189 A4S2F9 PAC:27413772 Ostreococcus lucimarinus 320  
Thecc1EG007964t2 A0A061E3X0 PAC:27460065 Theobroma cacao 303  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10673422
            12815595