GO Term : GO:0030906 retromer, cargo-selective complex GO

Namespace:  cellular_component Obsolete:  false
description  The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

2 Ontology Annotations

Class GO Term Gene Name Db
OntologyAnnotation GO:0030906 Zosma06g03740 GO
GOAnnotation GO:0030906 Zosma06g03740  

11 Parents

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0043234 protein complex A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
GO:0030904 retromer complex A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.
GO:0030906 retromer, cargo-selective complex The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.
GO:0044464 cell part Any constituent part of a cell, the basic structural and functional unit of all organisms.
GO:0032991 macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.
GO:0005575 cellular_component The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
GO:0005623 cell The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
GO:0098796 membrane protein complex Any protein complex that is part of a membrane.
GO:0044425 membrane part Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0012505 endomembrane system A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.

16 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0098796 GO:0030906
is_a GO:0044464 GO:0030906
part of GO:0030904 GO:0030906
part of GO:0032991 GO:0030906
part of GO:0005575 GO:0030906
part of GO:0043234 GO:0030906
is_a GO:0032991 GO:0030906
part of GO:0012505 GO:0030906
part of GO:0044464 GO:0030906
is_a GO:0005575 GO:0030906
part of GO:0044425 GO:0030906
is_a GO:0044425 GO:0030906
is_a GO:0043234 GO:0030906
part of GO:0005623 GO:0030906
part of GO:0016020 GO:0030906
part of GO:0098796 GO:0030906

5 Synonyms

Name Type
retromer complex, inner shell synonym
cargo-selective retromer subcomplex synonym
retromer, cargo recognition complex synonym
retromer CSC synonym
retromer, CRC synonym