Protein Domain : IPR026791

Type:  Family Name:  Dedicator of cytokinesis
Description:  DOCK family members are evolutionarily conserved guanine nucleotide exchange factors (GEFs) for Rho-family GTPases []. DOCK proteins are required during several cellular processes, such as cell motility and phagocytosis. The N-terminal SH3 domain of the DOCK proteins functions as an inhibitor of GEF, which can be relieved upon its binding to the ELMO1-3 adaptor proteins, after their binding to active RhoG at the plasma membrane [, ]. DOCK family proteins are categorised into four subfamilies based on their sequence homology: DOCK-A subfamily (DOCK1/180, 2, 5), DOCK-B subfamily (DOCK3,4), DOCK-C subfamily (DOCK 6, 7, 8), DOCK-D subfamily (DOCK 9, 10, 11) []. Short Name:  DOCK
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6 Child Features

DB identifier Type Name
IPR026796 Family Dedicator of cytokinesis 9
IPR026798 Family Dedicator of cytokinesis 6
IPR026799 Family Dedicator of cytokinesis protein 2
IPR026800 Family Dedicator of cytokinesis 3
IPR030717 Family Dedicator of cytokinesis protein 1
IPR031057 Family DOCK1 homologue

0 Contains

1 Cross References

Identifier
PTHR23317

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0005085 IPR026791
GO:0007264 IPR026791

2 Ontology Annotations

GO Term Gene Name
GO:0005085 IPR026791
GO:0007264 IPR026791

0 Parent Features

984 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
129262 D8T0J7 PAC:15417182 Selaginella moellendorffii 1772  
evm.model.supercontig_34.42 PAC:16417987 Carica papaya 930  
evm.model.supercontig_34.43 PAC:16417988 Carica papaya 150  
evm.model.supercontig_34.44 PAC:16417989 Carica papaya 157  
30024.m001742 B9RSI5 PAC:16815778 Ricinus communis 1844  
Cucsa.239810.2 PAC:16970816 Cucumis sativus 1835  
Cucsa.239810.1 A0A0A0K3K4 PAC:16970815 Cucumis sativus 1836  
orange1.1g000651m PAC:18135734 Citrus sinensis 1372  
orange1.1g000652m PAC:18135735 Citrus sinensis 1372  
orange1.1g001401m A0A067EH15 PAC:18135736 Citrus sinensis 1084  
AT4G16340.1 Q8SAB7 PAC:19647831 Arabidopsis thaliana 1830  
Thhalv10024194m V4MRI9 PAC:20195887 Eutrema salsugineum 1833  
Ciclev10010906m V4S6F9 PAC:20797181 Citrus clementina 1429  
Ciclev10010893m V4SQR7 PAC:20797180 Citrus clementina 1834  
Lus10013253 PAC:23166581 Linum usitatissimum 1736  
Lus10030776 PAC:23155267 Linum usitatissimum 1724  
Potri.004G000700.1 PAC:26991282 Populus trichocarpa 101  
Potri.004G000700.2 PAC:26991283 Populus trichocarpa 101  
Potri.004G000800.1 PAC:26991404 Populus trichocarpa 176  
Potri.011G024000.1 PAC:27001346 Populus trichocarpa 1848  
Potri.011G024000.2 PAC:27001347 Populus trichocarpa 1845  
Gorai.008G189300.4 A0A0D2T8M0 PAC:26814462 Gossypium raimondii 1786  
Gorai.008G189300.3 A0A0D2T2Y2 PAC:26814460 Gossypium raimondii 1843  
Gorai.008G189300.1 A0A0D2T2Y2 PAC:26814461 Gossypium raimondii 1843  
Gorai.008G189300.2 A0A0D2T2Y2 PAC:26814459 Gossypium raimondii 1843  
184770 PAC:27347681 Micromonas pusilla CCMP1545 2412  
31873 A4RXZ8 PAC:27416584 Ostreococcus lucimarinus 2055  
Thecc1EG011918t1 A0A061EB78 PAC:27463189 Theobroma cacao 1761  
Thecc1EG011918t2 A0A061EBD7 PAC:27463190 Theobroma cacao 1761  
Migut.H02557.1.p A0A022QR57 PAC:28951850 Mimulus guttatus 1845  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12432077
            15723800
            25022758