Type: | Domain | Name: | Moesin tail domain |
Description: | The ezrin-radixin-moesin (ERM) protein family link actin filaments of cell surface structures to the plasma membrane, using a C-terminal F-actin binding segment and an N-terminal FERM domain, a common membrane binding module []. ERM proteins are highly related members of the larger protein 4.1 superfamily. The sole Drosophila ERM protein, Moesin, functions in maintaining epithelial integrity by regulating cell-signalling events that affect actin organisation and polarity [].This entry represents the actin-binding tail domain of ERM proteins. | Short Name: | Moesin_tail |